Yes, I relate to that. In my case the difficulty is due to arthritis in the hands. What I do is disconnect while still in bed(for body stability and leverage), first I place the rubber glove on the bed as a spill protector, then I raise the tube to clear the tube of urine - either it goes into Bard or it goes into the pouch, then I hold the Bard connector with one hand while keeping the tip of the bag steady with the other, then I do a twisting motion.