Hi. I have Essential Thrombocythemia (high platelet count) without the JAK2 mutation. I've been under the care of a hematologist for 12 years and take Hydroxyurea daily for my ET. So far, this has worked to keep my platelet count normal, but the Hydroxyurea has the unfortunate side effect of destroying some of my red blood cells, thus, I must also take vitamin B12 and folic acid daily to counter this. That said, it simply isn't enough to counter the side effect and so my red cell count is always low and I'm anemic. However, I have done quite a bit of reading on foods for controling platelet count, especially pure unsweeted cranberry juice, which does lower platelet count. I have seen testimonies from people using this and they say that it is effective in maintaining normal platelet count (200,000 to 400,000). I am going to discuss this with my hematologist next week and see what he says about at least letting me try a one month trial in which I don't use the Hydroxyurea and, instead, use 8 oz. per day of cranberry juice instead. It is my hope that the cranberry juice will be sufficient to keep my platelet count below 400,000. If it can, then the B12 and Folic acid should create enough red blood cells to normailze my red cell count, as well. This would be a "win-win."