@eloise999 Yes I agree. I requested to see an MPN specialist and my hematologist asked me to give him 6 months to figure things out. I feel I am a bit ‘unique’ in that I don’t tolerate meds like a normal human should and in addition, he wants me to take a hormone blocker for the next 5 years to prevent a recurrence of the breast cancer. Oddly enough, my ET would have remained undiagnosed if the breast cancer dx came first. So do you ever have memory lapses and issues with recall? And how long did it take the side effects to subside after stopping HU?