Severe Adrenaline Spikes every morning - please help

Posted by jennabc @jennabc, Mar 22, 2023

Hello! I am absolutely desperate, so I decided to write on here, hoping anyone else has had a similar experience or has answers. For years, I have been struggling with what feels like intense spikes in adrenaline every morning. I have more severe and less severe months, but the more severe ones become so debilitating that I can’t function in life, and have become passively suicidal just to escape my physical experience. I’ve been diagnosed with anxiety and depression, but the weird part is that it feels so physical, it wakes me up from sleep, and no matter what I try to counter it (breathing, meditations, leaning into it, movement, medications, etc.), it persists until my body caps out on enduring the discomfort, and I fall into anxiety attacks and depression.

For some context, I have tried so many things. I have a history of EBV, HHV-6, SIBO, trauma, and PTSD. I’ve done tons of blood ozone and SOT for the first 3, and I’ve done/am still doing EMDR trauma therapy, regular therapy, ketamine infusions and lozenges, Neurofeedback, medications, I even exercise consistently, meditate, eat well, etc. I’ve been to an endocrinologist, who said tests looked good. I’ve gotten so much blood work over the years, and even my trauma therapist has said she hasn’t seen anything quite like this. She says it seems like my trauma is being processed and coming down, but that this physical experience will still spike and seem out of my control, making her concerned it’s a medical problem. I am desperate for help and answers. I don’t know how to fix this without knowing what’s wrong. Has anyone experienced or seen anything like this?
It wakes me up like clockwork at 7:30am, and even if I just lay there, I can feel it spike through my body, until it feels like my skin is burning sometimes, my stomach is dropping out, and I’m eventually squirming around in pain just hoping it goes away. I don’t know what else to do, please let me know if you’ve had or heard of anything like this, I will owe you my life.

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Profile picture for ready4vacation @ready4vacation

Thanks, Celia 16. So glad you received help and are doing better!!

Do you believe the episodes were related to hypoglycemia?

If you don't mind me asking, did your therapy focus on tools to help with nervous system regulation (like the vagus nerve / parasympathetic nervous system), or mostly talking things through?

Thank you for sharing!

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@ready4vacation , sorry for the delay in responding. I do not believe my episodes were due to hypoglycemia since I wear a continuous glucose monitor and always have a good idea of my blood sugar level. I can only describe what I experienced. It could be different from yours. My episodes came out of no where and weren’t related to any particular event. And, they felt different from panic attacks, because I had those many years ago for a short time. These were different.

To summarize, I was under a lot of stress, both personal and family. I had just been diagnosed with post covid syndrome and B12 deficiency. I did have some physical symptoms, but not related to my episodes. I saw neurologists, rheumatologist, endocrinologist, dermatologist, ENT, etc, It was overwhelming and stressful. I sought a therapist who had a medical/healthcare background. We addressed how I could manage my medical care, seek diagnoses, etc. with tools to help me find peace. I found that for me, there was a fine line between being a staunch advocate for my health and accepting diagnoses. He gave me feedback and support. My episodes decreased and became less intense . For me, I learned to accept that I had done due diligence in my healthcare and should go out and live my life. I also discovered how some family dynamics were impacting me negatively. He gave me confidence to address them, Gradually, I realized how much better I was. I am very grateful. I still have some issues for which I seek treatment, but it’s manageable.

I hope you can find answers and something that helps.

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Hi @jennabc did you ever find relief from this? I wake up between 5-6 am with the most intense symptoms that are horrible. Did you ever figure out what was causing it and how to fix it?

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Profile picture for austinga1 @austinga1

I too experience what feels like adrenaline surges early virtually every morning. It runs all throughout my torso, and is a horrible feeling. As someone who has never been an “adrenaline junkie” by choice, the fact that this seems to be something I have no control over leaves me feeling even more frustrated. It seems to come out of nowhere and for me, can last upwards of 5-10 minutes. If I find myself able to fall back to sleep, I am usually “gifted” with another dose of this invisible madness upon subsequent awakenings. I find that recently, my mind has been wondering if there is any damage possibly being done by these adrenaline dumps, or if it is only purely “mental”?

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@austinga1
100% my issue. I've been doing some research and may start taking Guanfacine and see how that works. Have you found anything that helps you yet?

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Profile picture for ready4vacation @ready4vacation

@hopscotch
Hi. It's now 2026 - three years after you posted. I hope you're feeling better. I'm writing because I'm having similar issues, though not as many spikes. Have you gotten to the bottom of this? If so, please share. In the meantime, here's my story, below. Please comment if you have any questions or you can provide any suggestions. Thank you so much!!

I have adrenaline or cortisol attacks every three hours during each and every day, and a couple times during the middle of the night before I wake. I've been dealing with this for 2 1/2 years, and not a single doctor (including several endocrinologists) can tell me what's going on. Does anyone else have this, or know what causes it?

When the attacks first started happening, I'd get frantic, almost like a panic attack - breathing fast, adrenaline surging, anxious, impatient, desperate, etc. Now, knowing the signs when they're coming on, I simply eat a plate full of protein, vegetables and complex carbs and that stops the symptoms fin their tracks, until precisely three hours later, when they come again. Occasionally, get brain fog if the symptoms arrive before I eat, and I can't think straight which is scary. I put my feet higher than my head and rest until I'm better. It's affected my quality of life, needless to say, and I need to have food with me at all times when the symptoms come.

Unfortunately, one endocrinologist insists these are panic attacks and wants me to see a shrink for some CBT. I've got a pituitary adenoma (and have had a few high cortisol tests, which the Dr. says is normal with stress, HRT, etc.). I don't have diabetes, though my a1c is creeping up as all this eating is causing me to gain weight. I've gained 30 lbs over this time.

I'm aware the "food" is the only way ""I"" know of to stop these attacks from causing who-know-what from happening. I don't know what else to do. Feels like I'm gonna die if I don't stop the feelings / attack.

Does anyone have issues like this, or know what this might be?

Thanks so much for your thoughts!

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@ready4vacation my cortisol has been fluctuating (sometimes high and sometimes low) when I get bloodwork. I started tracking my metabolic panel and noticed my glucose was getting higher when I would go into the doctor after a major “crash” -(when my body would feel so depleted and fatigued). I pointed it out and my endocrinologist has me wearing a glucose monitor now. It’s only been 3 days but I noticed my blood glucose usually hangs out around 70 (pretty low) but as soon as it drops it tries to self correct and shoots up and then within an hour or two crashes again. If I eat something sugary to correct the low it shoots up like crazy and then immediately crashes. However, I just noticed if I eat a small meal with carbs instead it has more of a gradual decline. My endocrinologist thinks it may be reactive hypoglycemia. She also suspects I have POTS. I’ve already been diagnosed with Sinus Tachycardia but my heart rate really spikes after meals. I actually feel better when I don’t eat. At first I was testing my blood sugar randomly when I felt bad with an at home finger prick kit, but it wasn’t until I got the glucose monitor that I noticed the food relation. Do you know if you have secondary high blood sugar? Or reactive hyperglycemia? I know cortisol and insulin are related and cortisol raises blood sugar. (And I know mine is kind of the opposite of what you are experiencing but maybe it can help you or someone else who reads this connect the dots. I’m still trying to connect mine too.) I hope you get some relief soon!

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