@pesquallie
"A study at Duke indicated that high testosterone is better if you have aggressive prostate cancer."

I got a little concerned when I read this as I am on a T-Blocker to reduce a recurrence of my cancer. Here is some context on the Duke study:

Yes, that is correct based on a September 2024 study from the Duke Cancer Institute, but with important context: it applies to specific advanced stages, not early-stage disease.

Key details:
The Mechanism: While low testosterone is used to slow early prostate cancer, Duke researchers found that in later stages, high-dose testosterone can force cancer cells to differentiate (mature) and stop dividing, reversing the growth stimulated by low-testosterone environments.
Bi-Polar Androgen Therapy (BAT): This approach, often called bipolar androgen therapy, involves rapidly cycling between very low and very high testosterone levels to treat castration-resistant prostate cancer (mCRPC).

Context: This is a therapeutic strategy for advanced, therapy-resistant cancer, not a general suggestion that high testosterone is "better" for all prostate cancer patients