@essiee I would strongly recommend trying low dose naltrexone again. There is a whole long covid support group of us using it on reddit and the Mayo Clinic support group who are having great results. I initially found it made me so tired I had to go to bed. I moved the dose from morning to night and did OK for two weeks. Then it gave me insomnia and I had to move it back to the morning...no sleepiness after that.

It works by temporarily blocking your opioid receptor causing your body to upregulate endorphins and regulates your microglial cells...giving you some anti-inflammatory pain relief and a little burst of energy to knock down any fatigue you have.

You need to start at a low dose, usually 2.5 mg, but some people need to start at .5 or even .1 mg. You increase very slowly until you get to a dose where your individual body feels good. My sweet spot is 5 mg in the morning...some people only need 1 mg a day or less. I have about 50% inflammation decrease with my dose and am considering splitting the dose to see if I can get more pain relief at night without the insomnia.