@pesquallie I have heard of Androgen resistant prostate cancer and it was one of the arguments I used with my Urologists who was skeptical about prescribing testosterone. My PSA goes down every time I do blood work so he has given up complaining.
That testosterone is rocket fuel for prostate cancer is something they came up with in the 1950's. Our medical system is slow to change when they are making money and those 3 month Lupron shots are over $5k. It's like Colonoscopy's, need it or not we will give you on because it is a big part of their profit.

@pesquallie
"A study at Duke indicated that high testosterone is better if you have aggressive prostate cancer."

I got a little concerned when I read this as I am on a T-Blocker to reduce a recurrence of my cancer. Here is some context on the Duke study:

Yes, that is correct based on a September 2024 study from the Duke Cancer Institute, but with important context: it applies to specific advanced stages, not early-stage disease.

Key details:
The Mechanism: While low testosterone is used to slow early prostate cancer, Duke researchers found that in later stages, high-dose testosterone can force cancer cells to differentiate (mature) and stop dividing, reversing the growth stimulated by low-testosterone environments.
Bi-Polar Androgen Therapy (BAT): This approach, often called bipolar androgen therapy, involves rapidly cycling between very low and very high testosterone levels to treat castration-resistant prostate cancer (mCRPC).

Context: This is a therapeutic strategy for advanced, therapy-resistant cancer, not a general suggestion that high testosterone is "better" for all prostate cancer patients