I'll keep it short. I was diagnosed with PCNSL in April 2015 and now 11 years later and up to this point (5/3/26) have been progression free. Treatment was the chemo only option of high dose Methotrexate and other drugs. Tumor looks like it just melted away on the MRIs in just a few months in 2015. I am so grateful that I have been progression free this whole time and frankly I don't deserve the good fortune, but I'll take it ! So there is hope !!! Internet says you are never out of the woods with this disease so yearly MRI's essential. For me the whole thing started with blurry/cloudy vision in my right eye. A vitrectomy removed the fluid from right eye with which they found out what kind of tumor I had. I went through several eye doctors before until I was sent to a high-end specialist. He found it when he said lets just do an MRI on your head just to eliminate unlikely possibilities !!! By that time I was having rapid cognitive decline although only 8 weeks earlier I was fine cognitively. Urgency is key here. I have a family history of autoimmune diseases and I got Crohn's disease around 2000 and immunosuppressants did not work and I had my entire colon and rectum removed 2007. I strongly suspect the immunosuppressants I took for the Crohn's disease may have brought on the PCNSL.