I had PMR a few years back and was treated succesfully (pred) for it. Recently, I had a mediport installed and the surgeon used a general anesthia on me. I woke up fine but soon had a PMR like (but much worse) reaction. Not wanting to take pred I dicided to tough it out-and no one would listen to me anyway. It was 4 days before it started to get better. Then it was over a week before I was normal. Told my PCP about it so it could be recorded.