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Living with Neuropathy - Welcome to the group
Neuropathy | Last Active: Jan 8 7:56am | Replies (6210)Comment receiving replies
Hi Colleen,
I have had Neuropathy in my left foot and left leg from stenosis. Tried many treatments and two lumbar laminectomies with little success. Now I have attended several seminars about stem cell treatments couple with other changes concerning meds, nutrition, laser treatments, EWOT, PNRT, vibration. Do you know if these treatments are effective or just failed treatments? Most of these treatments, even in combination are very expensive and most not covered by insurance.
Just something separate. How do I find responses to my posts when I return to this site?
Replies to "Hi Colleen, I have had Neuropathy in my left foot and left leg from stenosis. Tried..."
Hello @robertlclark
From your last sentence, I see that you want to find your previous posts. Is that correct? If so, just "click" on your username, @robertclark where ever it appears and it will take you to your Profile Page. If you scroll down that Profile Page, you will see all of your posts. You can click on "reply" and it will take you to the exact page where your post appears and you can see any of the other posts in reply to yours. Hope that is understandable. If not, @johnbishop can probably give better instructions. He is our teacher guru here on Connect.
Teresa
Thank you John, many companies are stating that they have successfully treated PN using stem cells.
@robertlclark you'll find more information about neuropathy and stem cells in this discussion on Connect:
– Stem Cell Therapy for Neuropathy https://connect.mayoclinic.org/discussion/stem-cell-therapy-for-neuropahy/
The short answer: Unfortunately, because of the complexity of the brain and spinal cord, little spontaneous regeneration, repair or healing occurs. Therefore, brain damage, paralysis from spinal cord injury and peripheral nerve damage are often permanent and incapacitating. It is very early days and research in neuroregeneration is ongoing. Beware of charlatans.
Connect
Hi @robertclark, I'm still trying to write up my notes from the recent MN Neuropathy Association meeting on Stem Cell Treatments but I do have one slide that sums up where stem cell treatments are for peripheral neuropathy. The last bullet is key to making stem cell treatment available for PN.
Outlook for treating peripheral neuropathy
* Stem cell transplantation remains largely at the pre-clinical trial stage.
* Proper stem cell homing and migration remain a concern.
* Stem cell transplantation has shown some benefit but is still inferior to nerve repair with conventional techniques.
* Pre-clinical and eventually clinical studies comparing different types of stem cell are needed.
* Optimal Schwann cell differentiation has yet to be achieved.
A little explanation for the last bullet:
The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration
-- https://www.cell.com/neuron/abstract/S0896-6273(17)30843-7
The repair Schwann cell and its function in regenerating nerves
-- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929314/
John