Gina,I understand your feelings .I had NTM presenting with the a 3 cm cavitary lesion. They wanted me on antibiotics for two years with a pick line doing some IVs. I could barely make two weeks and decided to consult a surgeon at NYU in Manhattan. I had a robotic lung Resection on March 2 and I am totally fine now. My pulmonologist did not suggest surgery, but I went forward in finding someone who would do it. This is all dependent on how your sister’s MAC presents. Please see if she may be a candidate for surgery and therefore not have to take antibiotics anymore .