My wife has had mild fibromyalgia most of her life, but never progressed until about 20 years ago. Now she suffers considerable from it. Approximately 15 years ago, a doctor prescribed Savella to her (she's now 74) and it worked great!! However, after several months of use (and total relief) the side effects abruptly hit her, shortness of breath, very elevated BP, and increased heart rate. After the 2nd time unfortunately she had to quit the medicine. It worked great, but side effects were, for her, too significant.
Now, since taking the covid shots (first 3, to keep her nursing license, then quit) she has developed severe migraines. Never had them until after the shots. The migraines are MUCH worse than the fibromyalgia.