I had a double positive ANA. 1:80 mitotic pattern & 1:320 nucleolar pattern. I have no answers even with having quite a few other test abnormalities & positive antibodies like ANA IgG, HEp-2 IFA, Anti-RA33 IgM, SM Ab. The closest thing to a diagnosis i have so far is autoimmune hepatitis, but it doesn't explain most of my symptoms & my numbers aren't high enough to give a concrete diagnosis. It's very... INFURIATING, to feel like absolute garbage, express to doctors how distressing this all is and have them compare your labs to a checklist and say, no but, your absolutely fine because your results don't add up to equal a diagnosis. I started questioning wtf was wrong with me in 2022 when the back to back severe upper respitory infections started, then the extreme fatigue, hair loss, rashes. It all peaked in 2024, when i ended up in the ER after multiple trips to my pcp and urgent care regarding something being wrong with my heart. I had a pericardial effusion, then liver abnormalities, then started coming down with "flu's" that never actually turned into the flu, just joint, muscle and bone pain, migraines and worsening fatigue. So far everyone agrees that I have autoimmune disease, that may just not have peaked yet, except for the person who has to make the diagnosis and treat it.