I started Sinemet 7 months ago, 1/2 pill for a month, then to 1 pill twice daily. I had nausea sometimes, but not all the time. Did not want to take extra Carbidopa, so I tried taking Sinemet when finishing my meal, standing up, and moving around for a while. If I feel nauseated, then I eat a pickle or a pickled palm heart. Usually, my nausea goes away. I don't know if what I did worked or if my GI system is gradually getting used to Sinemet.