(I had proton radiation at UC 5 years ago.)
There’s no way to know why your 3+4 became a 3+5.
> it may have been due to better sampling of the MRI guided biopsy.
> the “5” may have been there initially, just too microscopic to see.
> they may have simply missed it (given that Gleason scores are educated opinions).
As for pre-existing bowel issues, Dr. Rossi has information about this (& proton) in his portion of this 2023 Mid-Year PCRI presentation: https://www.youtube.com/live/WTqPnSRYtW4
—> Starting at about 4:48:15:
As for the “downside of radiation seems to be in 2 to 3 years some of the same side effects start to appear as surgery” depends on how much radiation overshoot there is that hits otherwise healthy nearby tissues and organs. Taking precautions in advance and during treatments is absolutely necessary.
(Diagnosed with prostate cancer in April 2012, I was on active surveillance for 9 years, I had proton radiation at UC five years ago (April-May 2021): 28 sessions (@ 2.5 grays per session) + 6 months (two 3-month injections) of Eligard. I also used SpaceOAR Vue. I also was not a candidate for focal therapy, having lesions on both sides of my prostate.)
For me - after years of research - proton beam was the right choice.
Best wishes on your decision.
@brianjarvis
Lots of truth in your post. The fusion guided biopsies are so good at hitting dead center of “target” that I believe the core samples describe disease state much better than the ultrasound only guided biopsies. Literally shooting in the dark many times. The present treatment protocols are based on historically old data, relatively speaking. So an old school biopsy may have discovered G3+4 and a treatment plan devised, while in reality the old school biopsy may have totally missed some G4+4 or higher that would move someone into another treatment protocol.
I perhaps make my present condition sound worse than it is. I am on no pain control or Flowmax. Just one 25mg Viagra as a penile protector while the rest of the Firmagon wears away. (55 day half life so it will be a while). Many mentions of incontinence here. I’ve never had that problem. Zero bowel issues.