@mayblin Once again, thank you for sharing all this info. So helpful. I know that Tymlos (and so Forteo, too) raises both P1NP and CTX, so stopping it would naturally bring them both down -- though, somewhere along the line I saw some data showing that it takes a few months at least for the CTX to decrease. Then, I guess, the HRT helped the process along and took over.

My gut always tells me that I want the P1NP to be higher, but I know the bone-remodeling process is tightly coupled between buildup and breakdown -- and hence that coupling between CTX and P1NP.

I will certainly share my endo's CTX target once I get it, but I won't be seeing her until November.