1. < Colorectal Cancer
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Anyone had Cetuximab and Encorafenib targeted therapy?

Posted by jd1010 @jd1010, Mar 30 11:43am

Husband diagnosed with BRAF (v600E) mutation after resected mestatic recurrence.
Colon surgery Dec 2023 and recurrence involving duodenal wall surgery February 2026.
Waiting on Guardant reveal test results. Dr has recommended targeted therapy. Has anyone received this? Please share results.

Interested in more discussions like this? Go to the Colorectal Cancer Support Group.

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Colleen Young, Connect Director | @colleenyoung | Apr 12 5:03pm

@jd1010, will your husband be starting encorafenib (Braftovi) and cetuximab (Erbitux)? How is he doing?

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jd1010 | @jd1010 | Apr 12 5:49pm

Hi Colleen - CT Scan clear and Guardant 1.8 after 2nd surgery. Primary onc wants to start him on C+E. 2nd opinion at MSK advised us to wait and see as he is now NED, but did say C+E is in his future. We are looking to be aggressive and hoping to stop it from recurring. Possibly do an online appointment with Mayo as we are getting conflicting advice? Just not certain if he should do C+E alone or with Folfiri? Now or wait?
It all seems a bit overwhelming and confusing. Thoughts? Thank you

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2 replies
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jd1010 | @jd1010 | Apr 12 5:49pm
In reply to @jd1010 "Hi Colleen - CT Scan clear and Guardant 1.8 after 2nd surgery. Primary onc wants to..." + (show)
Profile picture for jd1010 @jd1010

Hi Colleen - CT Scan clear and Guardant 1.8 after 2nd surgery. Primary onc wants to start him on C+E. 2nd opinion at MSK advised us to wait and see as he is now NED, but did say C+E is in his future. We are looking to be aggressive and hoping to stop it from recurring. Possibly do an online appointment with Mayo as we are getting conflicting advice? Just not certain if he should do C+E alone or with Folfiri? Now or wait?
It all seems a bit overwhelming and confusing. Thoughts? Thank you

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@colleenyoung

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Profile picture for Colleen Young, Connect Director
Moderator
Colleen Young, Connect Director | @colleenyoung | 13 hours ago
In reply to @jd1010 "Hi Colleen - CT Scan clear and Guardant 1.8 after 2nd surgery. Primary onc wants to..." + (show)
Profile picture for jd1010 @jd1010

Hi Colleen - CT Scan clear and Guardant 1.8 after 2nd surgery. Primary onc wants to start him on C+E. 2nd opinion at MSK advised us to wait and see as he is now NED, but did say C+E is in his future. We are looking to be aggressive and hoping to stop it from recurring. Possibly do an online appointment with Mayo as we are getting conflicting advice? Just not certain if he should do C+E alone or with Folfiri? Now or wait?
It all seems a bit overwhelming and confusing. Thoughts? Thank you

Jump to this post

@jd1010, if you would like to consider getting a opinion from Mayo Clinic experts, you can discuss with a scheduler virtual options.

Mayo Clinic welcomes both new and existing patients for virtual and in-person care in adherence with federal and state executive orders and guidance. Virtual care is available for out-of-state patients IF the provider you are seeing is licensed in the state where you live.

Video and phone visits can be great options for appointments before, after or in place of face-to-face care. Appointment coordinators will recommend a virtual visit if it best fits your individual needs.

Here is more information and how to get started with submitting an appointment request: http://mayocl.in/1mtmR63

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