@benedict66066 After the first year, I went off of the prednisone and mycophenolate was reduced to as low as I can go. So I am currently on Mycophenolate and Modified Cyclosporine. When my meds were changed, I felt better - more energy. Because each individual body is different - different meds work better in different bodies. For me, I have felt much better and my kidney function tests have remained strong - no change. My meds were changed approximately 2 and 1/2 years after my kidney transplant. So I have been on them for about 3 and 1/2 years.