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What exactly does low dose naltroxene (LDN) do for fibromyalgia?
Fibromyalgia | Last Active: Apr 22 1:39pm | Replies (39)Comment receiving replies
I am newly diagnosed for Fibro, suffered for the last 10 years the most (guessing I had it since I was 20yrs old).. making me change my whole life, leaving the job I loved of boarding and training horses for over 20 years, sold my farm and closed my business. I moved and saw drs in two states and was told I was getting "older" (turning 50) peri-meno (am not in), depression (not depressed, I'm mad at my body!) and all that. When I was diagnosed at Mayo in MN... I knew I did not want antidepressants. I researched LND and Tonmya.
I am on my 3rd week of LDN. I moved up to 3mg yesterday. I will say the 1.5 worked great for the first two weeks..it stopped all the buzzing in my body and I immediately felt better! I had to stop myself from overdoing it! When the pain is gone, the energy is back. But then I was finding it "wearing" off by 2-3pm... I would take flexeril then on bad overdoing it days.. or just motrin.
I feel alittle cloudy today on the 3mg, I'm sure its my body getting us to it.
I read people on here are starting it slowly, but my script has me to 4.5 in 3 weeks? 1 week 1.5mg, then 1 week, 3mg, and then 4.5. I hope that's not too fast? Also I hope my body doesn't get use to it too.. I guess we'll see how the 3mg works this week... cause if it works, I won't bump up yet.
I get it compounded at Avera in Sioux Falls, SD. They quoted me at 48 bucks for 30 day, 4.5mg.
Replies to "I am newly diagnosed for Fibro, suffered for the last 10 years the most (guessing I..."
@hendriksgal The buzzing in the body! I feel that and do not know how to describe it it. It’s not a chill, not something running through my veins. Feels creepy. Sometimes just centered in my pelvic area. But that’s what it is. Buzzing. Does anyone know what causes that?
I have tendency to google questions specific to me and get answers that way, and then I go to the sites from which their info came from.
When I just asked that question; their answer was from the National Institutes of Health and it said LDN treats fibromyalgia by reducing chronic neuroinflammation and boosting natural pain relieving endorphins; it works as a temporary opioid receptor antagonist, triggering a rebound effect that increases endorphin production, lowers pain signaling and inhibits microglial cells (immune cells) in the brain to reduce fatigue and brain fog.
I just research, dig and dig until I can make sense of everything for myself. And then I speak with my physicians about what I found and because I can provide them the sites that I retrieved the information from; it helps me. There are a lot of research papers out there and they matter.
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@hendriksgal I took a longer time to get to the 4.5mg dose, which was my choice. But my pharmacist advised me to take longer than three weeks. I didn't notice any positive benefits until I'd been on the maintenance dose for 1-2 months and then I had gradual improvement and today feel like I did before my symptoms flared up.
Looking back, I think I've had fibromyalgia for a long time, but it used to only flare up a couple times a year for 7-10 days, usually during the change in seasons. At that time, I thought it was the flu. Then a few years ago, it progressed to headaches, only on the left side of my head, that would last an about six weeks and then go away for about six weeks. I went to so many doctors for that and even had a biopsy of my temporal artery to rule out giant cell arteritis (GCA), which can be very serious.
When I got Covid in 2021, it triggered a major flare-up of body pain and I suffered with severe flares and terrible insomnia until I found LDN. I think it somehow triggered my immune system to get back to normal or something. I thank God every day for what seems like a miracle cure.