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@daisy17 thanks for the info. Unfortunately I am on a high dose, 40mg, of rosuvastain due to extremely high LP(a) levels. I cannot find a suitable bone loss drug that will work well with my other health issues. But I will bring this up with my endo next month. I wish they had better answers available about the impact on statins on bone health.
Replies to "@daisy17 thanks for the info. Unfortunately I am on a high dose, 40mg, of rosuvastain due..."
@llander1966 My step-daughter has the same issues with LP(a). I wonder if you can take a lower dose of a statin and add ezetimibe to help make up for the lower statin dose? I don't know...just a thought that maybe you can discuss with your Endo. I also read that metaformin may help boost osteoblast activity. Another thing to consider if you also have pre-diabetes or are overweight or are a full blown diabetic. I'm not a doctor so take everything I say with a grain of salt. I've just been looking at multiple studies regarding osteoporosis and these are just a few tidbits I came across. I wish there were better solutions.
@llander1966
I also have Osteoporosis plus very high Lp(a)-264- and all my treatable lipids have responded very well to mod dose rosuvastatin (10 mg) plus 10 mg Ezetamibe ( zetia). my cardiologist felt this combo best and avoids the high dose statin. My reading indicates no strong bone downside to this. Will of course keep reading….
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@llander1966 Me too. I get frustrated reading about possible BMD and fracture benefits from things such as statins, Fortibone, vitamin K and others that my doctors never mention.
One article I read on statins said 4 studies showed that low dose of statins improved BMD but had no fracture benefit, while 4 other studies showed BMD improvement and fewer fractures. So obviously more studies are needed. IMO, it doesn't matter if BMD is improved if it doesn't results in fewer fractures. But it doesn't appear there are more studies in progress.
I can't help feeling that if osteoporosis primarily affected men, more effort would be given to finding drugs that could help without the terrible side effects of the drugs currently available. The drugs would probably be cheaper too.