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DiscussionAnyone have testosterone replacement therapy (TRT) after ADT?
Prostate Cancer | Last Active: 6 hours ago | Replies (64)Comment receiving replies
Replies to "Has anyone selected Testosterone Replacement Therapy after ADT? If so, what were your results or recommendations?"
Has it been 2 years since the end of ADT? It can take testosterone a while to return especially with Lupron/Eligard. This decreases the probability of the prostate cancer coming back (testosterone below castrate levels is ADT without drugs). TRT will suppress natural testosterone production and recovery. Probably not an issue if there is none.
It has been 13 months since I stopped Orgovyx. My PSA is 0.03 and Total Testosterone is 52. I exercise regularly and lift weights 3 times a week in a semiprivate setting with no more than 5 other people. I don't have stable energy. sometimes I feel strong other times I need a break walking on a flat surface.
My oncologist is open for TRT. I think I will wait one more year before I consider TRT.
@stephenz, I moved your question to this related discussion so you can more easily connect with others who have considered testosterone replacement therapy after androgen deprivation therapy (ADT) for prostate cancer.
- Anyone have testosterone replacement therapy (TRT) after ADT?https://connect.mayoclinic.org/discussion/anyone-here-after-adt-undergone-trt/
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Depending on your case, many doctors will not recommend this since it can get the cancer growing again.
Once somebody has become castrate resistant, however, it can be used in large doses to kill off the cells that have become resistant.
There’s also a technique called BAT (bipolar Androgen therapy). It can be used in cases where people become castrate resistant and the drugs, no longer work for them. Getting on testosterone for a while can reverse that and they can get back on the drugs. It doesn’t work for everyone. Some people will have their PSA start to rise very quickly.
This newsletter has some real good information about BAT and a few other issues with treatment of prostate cancer.
https://online.flippingbook.com/view/150884930/2-3/
Here’s some more information about BAT
https://pmc.ncbi.nlm.nih.gov/articles/PMC9313844/