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@cathyf31 thanks for sharing those! It's interesting that your CTX increased slightly from baseline after that second (partial) dose of Evenity. Did adverse effects influence that dosing decision and, in turn (along with the bone marker info) lead to the switch to Tymlos?

As you know, Tymlos works by turning up overall bone remodeling process, which eventually affects both markers. Some doctors do tend to only check P1Np during PTH analog treatment (my endo did that until I nudged her to test both), but it's nice to get CTX alongside P1NP to see the full picture.

That jump to 93 in P1Np is a great sign. Hopefully you can gradually titrate up Tymlos to get the maximal treatment benefits. Wish you a successful journey.

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Replies to "@cathyf31 thanks for sharing those! It's interesting that your CTX increased slightly from baseline after that..."

@mayblin Thank you. Yes, unbearable and worsening side effects caused me to abandon Evenity. An overseas trip that coincided with the Tymlos denial/appeal and onboarding process caused the 2-1/2 month gap between Evenity and starting the Tymlos. Side effects caused the Tymlos adjustment down to 40 mcg (4 clicks). After 10 nights, I will be inceasing to 50 mcg tonight. Nobody wants me to titrate to a full days sooner than I do. However, my body does not have a history of cooperating. Expecting the best and being strategic with the titrating.