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← Return to High ISOPSA and PSA score?
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Did some research and was wonder how much further my concerns need be with this new information. I found the following from the National Firefighter Cancer Resource Center: Firefighters face an increased risk of prostate cancer compared to the general population, with studies suggesting they are diagnosed at a rate up to 1.21 times higher. This elevated risk is driven by exposure to carcinogens in smoke and firefighting foam, which can cause harmful changes to gene regulation (epigenetic modifications). Additionally my mom’s brother died of prostate cancer, and both my dad and his father had prostate cancer. I’m reading close family history increases the likelihood of cancer as well. Because of the triple whammy, does this increase my concerns? Please provide thoughts! Thanks 🙏,
Carey
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@careyp Concern should be on family history. One first degree (father, brother) male relative with prostate cancer doubles the risk that you will have prostate cancer.
If the MRI shows some PIRADs of 4 or 5 that also points to likely cancer. PIRADs 2&3 can be but usually are not (< 1/3) cancer. PSA can change up to 20% depending on lab methods. If the PSA has shown a steady increase over the last 6 years, there is a good chance that there is at least low-grade cancer. Was the 8.8 reported with the ISOPSA (these tend to be on high side) or done at the same lab as the 5.65? Sex or bike riding within 48 hours before the test also increase PSA.