Connect
← Return to What was Your P1NP Increase on Tymlos at 1 Month?
Discussion
What was Your P1NP Increase on Tymlos at 1 Month?
Osteoporosis & Bone Health | Last Active: Apr 24 3:31pm | Replies (38)Comment receiving replies
@cathyf31, it looks like you had a very brief course of Evenity (a couple of months?) before switching to Tymlos. It’s fascinating to see your P1NP response mapped out like this. The surge in p1np after transitioning to Tymlos is really impressive! Will you have follow-up btm labs to track Tymlos' progress? You mentioned you've had CTX tested twice as well. Would you be open to sharing those results? It will be interesting to see how your markers were moving together.
Replies to "@cathyf31, it looks like you had a very brief course of Evenity (a couple of months?)..."
Connect
@mayblin
Below is the info, including the CTX results. Please note that I only had one and a half treatments with Evenity and tonight will be my 29th Tymlos injection (19 full + 8 half-doses). I do not anticipate my doctor continuing to check CTX anytime soon, as Tymlos is not an anti-resorptive. Although, I haven't asked, as Tymlos is new to me for the past 1 month. I will try to remember to ask her about that next time I speak or message with her. Due to my side effects, she is testing more frequently than what I trust is typical. As soon as she started getting my results from my first round of blood & urine work at 3 weeks (all good), she told me she just submitted an order to repeat again in 3 weeks (just the CMP, P1NP, and iPTH).
Trending for P1NP
(Bone Formation Marker):
--------------------------
1) 08/28/25: Pre-Tx = 55
(CTX = 492)
2) 12/16/25: Evenity #1 = 85
3) 02/02/26: 1-Mo-Post- Evenity #2 (1/2 dose) = 52
(CTX = 544)
4) 04/13/26: Tymlos (19 full + 4 half injections) = 93