Does anyone have a solution to help manage Reclast side effects?

Posted by dingus @dingus, Aug 15, 2024

Does anyone have a solution to combat Reclast side effects. I had the infusion a year and a half ago and the side effects started shortly after I had the infusion. I still have weak legs, swelling in feet, pain in bones, dizziness (serious dizziness), cold sweats, tired all the time and nervous twitching in bones. Any suggestions?

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Profile picture for nycmusic @nycmusic

@ivstarter39 not a scientific response, but from reading posts here, Reclast is not an easy drug for many….and the side effects can last quite awhile…one wishes there was a test docs could do to see how well a patient might do…there are genetic and enzyme tests that oncologists use before initiating certain treatments and they are largely helpful.

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@nycmusic Hi, I have had at 3 infusions of Reclast. I guess I've been lucky, and have never had any side affects/reactions. I was diagnosed with Osteoporosis, but recently was told it hasn't done a thing fore me. Now, I need a hip replacement. My endocrinologist wants me to start taking Prolia. I am a kidney transplant patient, so I need to discuss this with him first. Has anyone taken Prolia and has it helped? Thank you

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auntymimi, https://pubmed.ncbi.nlm.nih.gov/39871033/
Prolia also has a good safety profile with kidney transplant patients. But you were on an antiresorptive for three years "that hasn't done a thing" for you. You might discuss this with your endocrinologist. You might also insist on bone markers to protect yourself against potentially harmful medications that aren't effective for you.
Forteo helps to integrate hardware used in hip replacement, and speeds healing. Be sure and ask the endocrinologist what medication would follow Prolia.
Best wishes for successful hip replacement.

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I had my first Reclape infusion two days ago. I live with severe fibromyalgia and Myfascial pain disorder. I will never due this again! My pain everyday ranges from a 6.5 to 8 . Within 12 hours my pain raised to a 9. It was in my ankles, feet , sheen bones, entire upper legs, hips and hands. Before my doctor said I would have a little joint pain. Are you kidding me?? I am so upset. What’s worse is the way chronic pain patients are treated, he only offered additional Tylenol. I’m sending him my hospital bill and he is fired! Think twice chronic pain warriors before you do this. Plus, were is the warning on Reclast site for those suffering in chronic pain?

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shudson, sorry you are having this pain. Some people have it for a week or so and then it goes away. Others are not so lucky. You might ask your doctor for a 5 day medrol pack. It is thought that the immune system can over react to the flood of zoledronate. No one wants to prescribe steroid to an osteoporosis patient, but I'm given to understand that the ongoing inflammation is more damage to bone than this short course of steroid. Around 30% of individuals taking Reclast have this painful reaction.
I suspect that anyone with autoimmune systems should avoid Reclast or insist on a lower dose with longer infusion time.
Did they do anything for you at the hospital?

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Profile picture for shudson @shudson

I had my first Reclape infusion two days ago. I live with severe fibromyalgia and Myfascial pain disorder. I will never due this again! My pain everyday ranges from a 6.5 to 8 . Within 12 hours my pain raised to a 9. It was in my ankles, feet , sheen bones, entire upper legs, hips and hands. Before my doctor said I would have a little joint pain. Are you kidding me?? I am so upset. What’s worse is the way chronic pain patients are treated, he only offered additional Tylenol. I’m sending him my hospital bill and he is fired! Think twice chronic pain warriors before you do this. Plus, were is the warning on Reclast site for those suffering in chronic pain?

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@shudson hopefully you are starting to feel better! Once it’s in your system, I’m finding, It’s there for a long time. Do not mean to discourage but I’ve been 22 months, a little better but far from where I was before the infusion!

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