Connect
← Return to What was Your P1NP Increase on Tymlos at 1 Month?
Discussion
What was Your P1NP Increase on Tymlos at 1 Month?
Osteoporosis & Bone Health | Last Active: Apr 24 3:31pm | Replies (38)Comment receiving replies
@gently Yes!! I've had the P1NP tested 4 times, since my osteoporosis Dx last summer (Aug. 2025). First time by my PCP, so endo could have as much info as possible on my first visit. CTX has been tested twice....baseline and while on Evenity.
P1NP (Bone Formation) Trending
----------------------------
1) 08/28/25: Pre-Tx = 55
2) 12/16/25: Evenity #1 = 85
3) 02/02/26: 1-Mo-Post- Evenity #2 (1/2 dose) = 52
4) 04/13/26: Tymlos (19 full + 4 half injects) = 93
Replies to "@gently Yes!! I've had the P1NP tested 4 times, since my osteoporosis Dx last summer (Aug...."
Connect
@cathyf31, it looks like you had a very brief course of Evenity (a couple of months?) before switching to Tymlos. It’s fascinating to see your P1NP response mapped out like this. The surge in p1np after transitioning to Tymlos is really impressive! Will you have follow-up btm labs to track Tymlos' progress? You mentioned you've had CTX tested twice as well. Would you be open to sharing those results? It will be interesting to see how your markers were moving together.