@animate
When my PSA hit .2 3 1/2 years after my prostatectomy, I was put on a six month Lupron shot and Two months later had salvage radiation. I was a 4+3. The reoccurrence is one reason they like to put you on ADT to prevent further reoccurrences after. I never even noticed there were side effects to the Lupron shot. I went to work every day in my consulting business, and it didn’t slow me down at all. I am, however, one of the people that never had fatigue from any of the drugs. They didn’t know at the time I had BRCA2, That’s the reason it keeps coming back.

My brother was a 4+3 and decided on SBRT radiation. Again they gave him Lupron two months before treatment and then one more three month shot when the first one expired. He was 77 at the time and it was no big deal. His biggest problem was the hot flashes.

Different people have different reactions to ADT, Don’t be too afraid of a six month shot.