@dks2500 My husband had his BCG at a local cancer center, under the direction of his Mayo urologist. We live 10 hours away from Rochester. He had no issues with the treatment other then a short lived increase in frequency of urination for 24 hours. The catheterization was smoother when the nurse infused lidocaine gel initially. At the time there was rumor of shortages but it was always available at this treatment center. Unfortunately he had a relapse during the maintenance phase of his BCG treatment so was considered a BCG failure. With a highly aggressive cancer, he did end up with radical cystectomy/neobladder but is cancer free.

@dks2500 I had a course of six BCG treatments in Omaha during the spring of 2024. BCG then became unavailable locally (April 2024). The treatments were at my urologist's office, and went off without a hitch. I had nine months of Adstiladrin treatments in 2025-2026, when the cancer returned, and now am hearing into another course of 12 BCG treatments in May-June. My treating physician is now at Mayo - Rochester, and he has assured me Mayo has a steady supply of BCG that will not be interrupted. Actually, Mayo has recombinant BCG (rBCG), which is an engineered version of the traditional Bacillus Calmette-Guérin vaccine, modified to enhance immune response for treating non-muscle invasive bladder cancer. I will do my treatments here, at an infusion center or my local urologist's office, if the rBCG is available locally; otherwise, I'll drive to Mayo for the treatments. Best of luck to you.