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Can Orgovyx be prescribed with Nubeqa for Gleason 9 patient who has localised prostate cancer?
Medical oncologist for my husband said Nubeqa is prescribed for metastatic cancer only. Is that true?

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Replies to "Can Orgovyx be prescribed with Nubeqa for Gleason 9 patient who has localised prostate cancer? Medical..."

@ambika Yes, but that is off label since the label says for local should be castrate resistant (means Orgovyx no longer works). Problem will be getting insurance coverage off label in USA for drug with list price over $12K per month. Will probably want to start step therapy with Zytiga since it is a low-cost generic. Side effects much worse but has same clinical effect as Nubeqa.

@ambika
At this time, it is prescribed for metastatic, castrate sensitive prostate cancer. If it’s not metastatic, then it’s not approved yet.

Usually, they will prescribe Erleada (apalutamide) In that situation.