@nasbyevan - welcome to Mayo Clinic Connect. That is interesting that carbidopa- levidopa (C-L) brings relief to your calf cramps and stiffness.

I wanted to tag @wkrebs59 and @hopeful33250 to see if they may have heard of off-label usage of C-L like this, and especially in younger adults?

nasbyevan, did your doctor give you a diagnosis for your calf issue? If so, what was the diagnosis?