@gingerw
Check ingredients and supplements and medications.. There could be something in the supplement and medication’s that she is sensitive to.
For eight months, I was taking a calcium citrate never gave it a second thought, but within a few days after starting it, I developed hives. You talk about pain and they were all over my body.. One day, my doctor said I wish I could figure out what chemical is. I went home, check the calcium citrate, and the very first item was a form of grain alcohol that I am highly sensitive. Two months later, the hives are almost gone, but I’m still having an outbreak. I wish you the best and figuring this out