HRT Safety

Posted by debbie1956 @debbie1956, Jun 8, 2024

I wanted to share this Medscape article I received today about new study on HRT. I am considering HRT for my osteoporosis at age 67 and am so encouraged by this article: https://www.medscape.com/s/viewarticle/hormone-therapy-after-65-good-option-most-women-2024a10007b2

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

Profile picture for debbie1956 @debbie1956

Thanks for recommending "Great Bones", Yes I have read the entire 700 page book which was worth every page! That book has a vast amount of vitally important information I couldn't navigate this situation without. I know Keith McCormick doesn't promote HRT for women my age, with such low score and recommends it for prevention rather than regaining. There seems to be new information lately about the benefits and safety of HRT even for women long past menopause. I recently watched an interview with McCormick in which he states he has changed his position somewhat on HRT. I'm not hopeful the HRT can reverse my loss but hope it may stop the progression. My REMS Echolight fragility score showed incredibly that my bone quality was still on the border of green zone low fracture risk which may explain the mystery of why I haven't fractured yet with spine at -3.5! The REMS results were similar to DXA at -3 spine and -2.6 total hip compared to DXA at -3.5 spine and -2.5 total hip. I'm hoping with some quality of bone remaining and avoiding a fall I may be able to cope. I hope to start HRT in the near future with naturopath who specializes in it and menopause, but haven't consulted with her yet so not sure what she will recommend. I will have another DXA in 6 months, a year from my last. The internal medicine doctor from the Osteoporosis Clinic in Vancouver recommended Evenity which is at least an anabolic I would want. I would have wanted Tymlos if I chose a medication, but it appears Tymlos isn't available in Canada. I have read many of your posts on Tymlos which have been so informative and helpful for me. Thank you so much for sharing all your experience. The doctor said Forteo is available for a mere $12,000.00 a year! Evenity costs $8000.00. But even the cost is not my first reason for wanting to try all my options first. I may eventually book a video appointment with Keith McCormick if he still offers this. (Far less expensive than the medication costs!) Thank you again for responding.

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@debbie1956 I haven’t read this entire thread, my apologies on that, but am fascinated by your story and am wondering if you have posted an update on what you chose to do? Evenity? Some type of HRT-what are or were your options? Any success or improvements on your Dexa scores?

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Profile picture for gerrirose @gerrirose

Any reason to not be able to take hrt at age 82?

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@gerrirose check out Louis Newsom's podcasts. She is a doc in the UK. Her latest talk is HRT after 55

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Profile picture for gerrirose @gerrirose

Any reason to not be able to take hrt at age 82?

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@gerrirose sorry I spelled her name wrong. It is Dr Louise Newson.
NewSON, not NewSOM.

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Profile picture for patwerthman @patwerthman

@debbie1956 I haven’t read this entire thread, my apologies on that, but am fascinated by your story and am wondering if you have posted an update on what you chose to do? Evenity? Some type of HRT-what are or were your options? Any success or improvements on your Dexa scores?

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@patwerthman
Thank you for responding to my post. It's amazing for me to read it again. It's been quite a journey after two years. After a lot of research and consultation with others, I opted for the BHRT at age 67 almost two years ago. I found a Menopause Society certified functional medicine doctor who prescribed it after assessing me for risks. My CTX was at 688 before the BHRT and decreased to 138 when I retested 8 months later, so my bone resorption rate was greatly reduced. My REMS Echolight showed a slight gain from spine -3 to -2.6 also 8 months later. I was also taking supplements and following diet recommendations by Keith McCormick which may have played some part. I am still on the Estradiol .025 patch with micronized progesterone 100 mg nightly. I have no negative side effects, just mild feeling of calm and better sleep. I am due for another Echolight and DEXA so will see how things are holding up. Just stopping the progression of bone loss was a big win for me, so the slight gain was a big bonus!

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Profile picture for debbie1956 @debbie1956

@patwerthman
Thank you for responding to my post. It's amazing for me to read it again. It's been quite a journey after two years. After a lot of research and consultation with others, I opted for the BHRT at age 67 almost two years ago. I found a Menopause Society certified functional medicine doctor who prescribed it after assessing me for risks. My CTX was at 688 before the BHRT and decreased to 138 when I retested 8 months later, so my bone resorption rate was greatly reduced. My REMS Echolight showed a slight gain from spine -3 to -2.6 also 8 months later. I was also taking supplements and following diet recommendations by Keith McCormick which may have played some part. I am still on the Estradiol .025 patch with micronized progesterone 100 mg nightly. I have no negative side effects, just mild feeling of calm and better sleep. I am due for another Echolight and DEXA so will see how things are holding up. Just stopping the progression of bone loss was a big win for me, so the slight gain was a big bonus!

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@debbie1956 Thank you VERY much for this information. I didn't even know this could be a possibility!!!

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Profile picture for debbie1956 @debbie1956

@patwerthman
Thank you for responding to my post. It's amazing for me to read it again. It's been quite a journey after two years. After a lot of research and consultation with others, I opted for the BHRT at age 67 almost two years ago. I found a Menopause Society certified functional medicine doctor who prescribed it after assessing me for risks. My CTX was at 688 before the BHRT and decreased to 138 when I retested 8 months later, so my bone resorption rate was greatly reduced. My REMS Echolight showed a slight gain from spine -3 to -2.6 also 8 months later. I was also taking supplements and following diet recommendations by Keith McCormick which may have played some part. I am still on the Estradiol .025 patch with micronized progesterone 100 mg nightly. I have no negative side effects, just mild feeling of calm and better sleep. I am due for another Echolight and DEXA so will see how things are holding up. Just stopping the progression of bone loss was a big win for me, so the slight gain was a big bonus!

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@debbie1956 , this is good news. May I ask what tests were done to assess risks?

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Profile picture for debbie1956 @debbie1956

@patwerthman
Thank you for responding to my post. It's amazing for me to read it again. It's been quite a journey after two years. After a lot of research and consultation with others, I opted for the BHRT at age 67 almost two years ago. I found a Menopause Society certified functional medicine doctor who prescribed it after assessing me for risks. My CTX was at 688 before the BHRT and decreased to 138 when I retested 8 months later, so my bone resorption rate was greatly reduced. My REMS Echolight showed a slight gain from spine -3 to -2.6 also 8 months later. I was also taking supplements and following diet recommendations by Keith McCormick which may have played some part. I am still on the Estradiol .025 patch with micronized progesterone 100 mg nightly. I have no negative side effects, just mild feeling of calm and better sleep. I am due for another Echolight and DEXA so will see how things are holding up. Just stopping the progression of bone loss was a big win for me, so the slight gain was a big bonus!

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@debbie1956 my endocrinologist won’t prescribe HRT. Im 69 she says it won’t help my bone loss much at this point, although I could certainly use the other benefits it provides.
Maybe my blood pressure is an issue with HRT as well. I’m going to revisit this with another MD next month.
Thanks for your insightful post. Best of luck. I think the spine improvement is a win. I’ve been struggling to stay on Tymlos so far 7 months. No idea what else I will even take after or instead of. They suggest Prolia…..I can’t take oral biophosphates. I exercise a lot.

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Profile picture for debbie1956 @debbie1956

@patwerthman
Thank you for responding to my post. It's amazing for me to read it again. It's been quite a journey after two years. After a lot of research and consultation with others, I opted for the BHRT at age 67 almost two years ago. I found a Menopause Society certified functional medicine doctor who prescribed it after assessing me for risks. My CTX was at 688 before the BHRT and decreased to 138 when I retested 8 months later, so my bone resorption rate was greatly reduced. My REMS Echolight showed a slight gain from spine -3 to -2.6 also 8 months later. I was also taking supplements and following diet recommendations by Keith McCormick which may have played some part. I am still on the Estradiol .025 patch with micronized progesterone 100 mg nightly. I have no negative side effects, just mild feeling of calm and better sleep. I am due for another Echolight and DEXA so will see how things are holding up. Just stopping the progression of bone loss was a big win for me, so the slight gain was a big bonus!

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@debbie1956 Sounds like good news for you. I too have just started BHRT at 68. A chiropractor suggested it to me a few years ago, but I declined. After my second DEXA got worse with a lot of supplementation and exercise, I went the BHRT route. The MD that prescribed it for me specializes in hormones and also does surgical procedures such as face lifts,tummy tucks etc. She also switched my thyroid medicine from Synthroid (25 years) to NP Thyroid. After 2 weeks on the BHRT and NP, I can say I feel wonderful. Great sleep and less agitated at the world. Maybe placebo, but I'll take it after feeling like a tightly wound clock since I started the synthroid at 52! My Dr did a CBC and CMP, plus asked about family history.(no cancer history in my family) The only med I took was the Synthroid. I was very hesitant to switch to the NP, but I feel a big difference and am sleeping better. Exercise and good diet are still imperative. I never was a smoker, which is really bad for bone density. Alcohol is also detrimental. Good luck to us all on the bone journey.

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American Heart Association article on Hormone Therapy.

Rethinking Menopausal Hormone Therapy: For Whom, What, When, and How Long?
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.061559

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Profile picture for leeosteo @leeosteo

@debbie1956 , this is good news. May I ask what tests were done to assess risks?

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@leeosteo Sorry for my delayed reply. I just discovered your message in my inbox. The tests the Menopause Society physician looked at were my cholesterol and A1C levels, blood pressure as well as CBC test results. She recommended a coronary artery scan as well which I had done. All my results were fine with a coronary artery score of zero. She also weighed me and asked about family cancer history etc.

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