@synthiame Hi, I'm not sure if I told you that I also see a neurologist. I was waking up with a headache every single morning at around 5 a.m. The only thing that has helped is when I started duloxetine (Cymbalta) which can help with nerve issues as well as anxiety. I had read that it can help taste issues so I asked to try it. It has lessened the taste disorder about 25% but I need it to be better than that. The neurologist has run every test available too. All kinds of blood tests, even for Lyme disease and heavy metals but the only thing found was Sjogren's which I already knew. The EEG and MRI's were all normal so it's still a mystery. I would love to try the oral probiotic that you are on to see if it helps. Can you give me a name of what you are now trying? I take a general probiotic but I have been on it for years. Yes, I think too that I will always have this taste disorder because of the Sjogren's. I would like to figure out at least how to make it bearable. Today I was okay in the morning and then we went to Costco. They had some samples out and as soon as I had them the sour/bitter taste started. It takes just about nothing to set it off!! I do have an irritated tongue all the time but it's the tip of the tongue. The dentist says it should not be causing this problem but I do not have an abnormally white tongue. Everytime I go to the dentist I ask her if my tongue looks okay and she says Yes, which is good but not good because it sure doesn't act okay!!! Gum seems to work to at least make the day bearable since the pilocarpine didn't really help me. Okay sorry this reply was so long!!!