Gabapentin 300mg: what are the short and longterm effects?

Posted by brainhealth @brainhealth, Dec 26, 2025

What are the short and long term effects of taking this medication?
Please discuss if it has helped others to calm overactive nerves and/or any risks.
The medication was prescribed to calm overactive nerves.

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Profile picture for bobrogers @bobrogers

I was on that medication threw them in the trash very dangerous drug didn’t know if I was walking forward are backwards could not think are drive stay away if possible

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@bobrogers A lot of these drugs are dangerous & have terrible s/effects. I have refused a lot of medications for Osteoporosis & seizures caused by a TBI, some Drs have refused to see me again to even try to discuss an alternative treatment.

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I have superficial siderosis. It has caused nerve damage. I was on 900 mg every night. No side effects. Also no side effects for going off of it. Please see Mayo Clinic/Steve GRINSTEAD about a news. Paper article about. SS. I hope and pray the best for you.

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I take 800mg, 3 in the morning and 2 at night. It's a high dose but it controls my psychogenic tremors caused by severe PTSD. I've been on this dose since 2012 and had NO side effects in all these years. I've had to explain to any new doctor that I don't have nerve pain or neuropathy because it is not well known that Gabapentin has other uses. If I didn't take this dose amount I'd look like someone with Parkinson's. It's been a miracle drug for me

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Profile picture for burchy2026 @burchy2026

Can I ask what quantity of Gabapentin you take?
I am taking 2700 a day at 900 intervals it for nerve damage due to Shingles last year

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@burchy2026
If you were asking me what quantity of Gabapentin I am taking, I'm taking 300mg three times a day.

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Profile picture for wilmslow @wilmslow

@burchy2026
If you were asking me what quantity of Gabapentin I am taking, I'm taking 300mg three times a day.

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@Did you start on that low quantity or have you reduced down to that because this is what I am find difficult.
I need to come of them .
Anne

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I started at 200 mg three times a day but after a month I had to move up to 300mg. Since then, 300mg seems to keep my symptoms under control for the most part.

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Please be very careful when taking Gabepentin, even small doses. This medicine has some nasty side effects. Studies have shown that even a small dose can massively raise your risk of getting dementia. The Studies have also shown that the longer you are on Gabepentin, the higher your risk of getting Dementia. It's not called Garbagpentin by chronic pain suffers for nothing. It's partner Lyrica is also starting to show that it too raises your risk for dementia. And whatever you do don't let your dr. Proscribe Subloxone. This medicine, even at a low dose has been proven to cause massive dental issues. So much so that it can cause you to lose all your teeth.
I know as a chronic pain sufferer (several conditions) that there isn't much in the way of medications that help to lessen the pain we are in on a daily basis, so if you are able to avoid taking any of the above mentioned prescriptions thats great. But if you have run out of medication
Choices and the ones mentioned above your only choices, start with Lyrica as it doesn't have as high a dementia risk as Gabepentin. If you have to take Gabepentin or Lyrica because nothing else has worked, try to keep the dosage to the barest minimum that helps to control the pain. The higher the dosage of Lyrica or Gabepentin you take, the higher your risk of developing dementia is. If your dr. is pushing you to take one of the above mentioned medications, take a step back and do your own research on these medications. Check out Facebook groups about your particular diagnosis as well. Many of the members of these groups have already been in the position you currently find yourself in. Talk to the members in the group. It is one thing to take advice from a doctor who has never had to go through what you are currently experiencing, it is something else entirely when you speak to others who are going through the same type of health issues you are. The doctor gives you their opinion based on their medical knowledge while the members of a Facebook group give you their opinions based on lived experiences. Once you have done your own research on the medication, gotten your doctor's opinion on the medication he wants to prescribe you and the lived in experiences with the medications from the members in your Facebook groups, you will be able to make an informed decision as to what is best for you in that moment. Just remember to take the doctors opinion about the drug with a grain of salt. Many doctors have agreements with the Big Pharmaceutical companies to push their medications over others(they aren't supposed to but it still happens more often than the public realizes). Please explore what other medications (drugs, supplements) or other types of alternative treatment (Osteopath, Massage therapy, acupuncture etc) could be tried before agreeing to take Gabepentin, Lyrica or Suboxone. If nothing else has helped an you do end up having to take Gabepentin, Lyrica or Suboxone, start at the lowest dose possible and keep a record of when the drug was taken, any side effects you may have and did or didn't the drug help with your symptoms.

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Profile picture for laura @laura1961

@bobrogers A lot of these drugs are dangerous & have terrible s/effects. I have refused a lot of medications for Osteoporosis & seizures caused by a TBI, some Drs have refused to see me again to even try to discuss an alternative treatment.

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@laura1961 good, i don't take any FDA drugs either they all have terrible side effects, you hear all those commercial for drugs where they say you can even die from it, baffles me how ppl can take those. A friend took a pill for a year for Osteoporosis and when the Dr see her again it did nothing. I go to the Drs and if they give me a drug to take and don't say anything and never fill the prescription, i take natural supplements

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Profile picture for khali @khali

@laura1961 good, i don't take any FDA drugs either they all have terrible side effects, you hear all those commercial for drugs where they say you can even die from it, baffles me how ppl can take those. A friend took a pill for a year for Osteoporosis and when the Dr see her again it did nothing. I go to the Drs and if they give me a drug to take and don't say anything and never fill the prescription, i take natural supplements

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@khali Yes I do the same.

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I don't think the answer is refusing to take any medications at all. True, some medications do have side effects that can cause problems for some people, but what doesn't work for one person might work for another person without any side effects. If I didn't take Gabapentin I wouldn't have much of a life.

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