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Trying to decide on treatment for prostate cancer

Prostate Cancer | Last Active: Apr 12 10:36am | Replies (38)

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Profile picture for Jeff Marchi @jeffmarc

@heavyphil
I know so many people that went with five sessions of SBRT radiation to treat their prostate, Including my brother at 77. It’s a very common technique. Many people also used proton instead of photon for those five sessions. Adding HDR to that is not that revolutionary. Combining HDR brachytherapy With IMRT is very common.

I just don’t see a risk to combining those two things since SBRT is used so much. Dr. Roach at UCSF Uses that almost exclusively. He speaks at a number of conferences about it.

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Replies to "@heavyphil I know so many people that went with five sessions of SBRT radiation to treat..."

@jeffmarc So the purpose of this clinical study is…what?? To see if we can mix electrons and protons?
HDR+ IMRT or SBRT is already used frequently and is fairly successful.
So I have to assume that the proponents of proton therapy want to show that protons are equally - or more - effective than photons when used in combination therapy. Time will tell. Best,
Phil

@jeffmarc @heavyphil
im a high risk guy, about to start orgovyx and then apalutamide (Luminal B cancer), which seems right based on my research. Im debating on the type of radition. Would like the convenience of 5 dose SBRT, but is there is enough data to justify this? Ive seen some promising info, but dont think it is standard care. Because of my risk factors, I need to radiate the pelvic lymph nodes as well as pelvic bed. i have read the larger the area, the more you should spread out the sessions. And the whole proton debate continues with competing arguments.

Your input would be appreciated. PS Decipher .93 (.75 post surgery), cribiform, EPE. no vesicles, nodes (but only 3 dissected). Pre surgery PSA 5, post uPSA .069, .039. .036, .056, .051 every 6-8 weeks. Apprehensive!

Last, looking for a experienced high risk RO for second opinion. Any references would be great! Currently working with Dr. Daniel Song at JHU.