Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Posted by dougs72 @dougs72, Jun 22, 2024

Has anyone ever been on Duloxetine (Cymbalta) for nerve pain? I've had 2 doctors push this on me. I know that the side effects can be terrible and getting off of it difficult as it requires titration. One time I remember taking one pill, and not liking the way it made me feel, so not taking any more, and still feeling the "weirdness" from it 2-3 days later. and that was only 30 mg Please pass along any experience or advice from this medication?

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Profile picture for kimithy @kimithy

@nanniesue4
Oh I can sympathize with you. I saw several back surgeons and the last one told me that fusing was an old way of taking care of back pain, but it didn’t always work and sometimes you are still left with the pain!
I had met with two other surgeons that were ready to slap some hardware in me. I just kept thinking there’s gotta be a better way.

The last surgeon in Walnut Creek CA told me not to let anyone fuse me. He told meto be on a comfortable stationary bike that supports your back and hips so it has to have a back on it and to be on the bike 15 minutes a day for the rest of your life. I suggest you invest in a comfortable stationary bike.

Have you tried an inversion table to decompress your neck?
Or seek manual help where someone holds your neck at the base with their fingertips on the base of your skull and slightly pulls to release tension and tightness.

I would suggest a neck cradle that you attach to a door knob and you lay on the floor and you put your neck in this cradle to help you leave the pain in your neck.

If you can’t find a cradle, then you can get a rope and tie a tea towel on both ends of the rope and put the rope over the door knob and then put your head in the cradle and move out enough to where your head can swing freely. I hope this makes sense to you.

I hope this helps.

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@kimithy i have never heard of this neck cradle before going to try this thank you!

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Profile picture for rosac @rosac

Cymbalta caused insomnia right from the start. I don’t want it! Not taking!

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@rosac I understand it also is very addicting and you have to cone off it slowly because it will cause addiction problems. And on top of that it causes weight gain so I have gained 30 lbs and that can’t be good either. It so hard to know what to do.

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Profile picture for Nanniesue4 @nanniesue4

I have been on both from my family Doctor and I am no better. I feel emotionally nothing. I cannot cry as I have Sojourns disease and have no tears. So I find a spot where no one hears and scream. Thats my coping mechanism. 3 auto immune diseases and am in pain most of the time. Just had another fusion in back hook up to another fusion now that makes 4 fusions. 5 surgeries in my back. I fell in 2024 backwards and had another lower surgery lower. But my neck is what hurts the most neck shoulder wrist thumb and pointer finger. Which should be C6 but I already have a fusion in C567 so as the neurologist 2 of them and 2 orthopedics doctors says there is nothing causing the pain. A bit of confusion. So today I see a hand Dr. because it can’t be from my neck. Its already fused and no one want to be responsible for something goes wrong. So here I sit telling my story of painful broken overweight body that has plagued me for many many years. I have no answers. Its just my life.

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@nanniesue4
I’ve been on Cymbalta for a few decades. For me, it helps with the pain and depression, but I noticed I feel very flat emotionally most of the time.
I’m so sorry for your multiple surgeries and problems. It’s clear that cutting further may not be the answer.

After multiple spine surgeries and the generalized pain from psoriatic arthritis, I’ve decided to pursue other modalities to deal with it: massage, visits with a pain psychologist, physical therapy, walking and exercise as much as the pain will allow, and surrounding myself with understanding friends and family. I hope you will find the answers for your disability. It doesn’t mean I’m pain free. It just means I’m heading in another direction. Every time a surgeon cuts on me, I feel like I’m laden with more problems than before. Enough already.

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Nerves hurt when their myelin is eroded . Vitamin B12 restores myelin. Most people's diets are very low in B12 food i.e. animal protein. Best thing to do is take lots of COBALAMIN. That's the fancy name for B12.
Go for it.

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I had the same experience. I only took 2 doses. I had brain fog, was dizzy and just felt unwell. I did not continue with it. I am currently on gabapentin. I have been unable to titrate up higher than 400mg per day. I take 100mg in the morning and 300mg at night. I think it helps with night time nerve pain. Higher doses made me feel unable to function or drive (my husband depends on me to drive). As with Cymbalta, I get brain fog and feel very lethargic if I take a higher dose.

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Profile picture for siggy50 @siggy50

I had the same experience. I only took 2 doses. I had brain fog, was dizzy and just felt unwell. I did not continue with it. I am currently on gabapentin. I have been unable to titrate up higher than 400mg per day. I take 100mg in the morning and 300mg at night. I think it helps with night time nerve pain. Higher doses made me feel unable to function or drive (my husband depends on me to drive). As with Cymbalta, I get brain fog and feel very lethargic if I take a higher dose.

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@siggy50
I’ve been on Cymbalta for about 2 years. Does nothing for nerve pain but does help my mental mood. Everyone reacts to the same drug differently sometimes. Talk to your doctor.

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I was prescribed Cymbalta for nerve pain/depression. I got a bad headache. I stopped for a week and tried again, and the same thing happened. I went back to Lexapro.

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Profile picture for yram @yram

Yes I got dizzy and had brain zaps from coming off 330 mg of cymbalta. It didn't help the pain.

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getting off it was a nightmare and it took 4 months for the brain zaps and nausea to abate.

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I have been trying to titrate down from duloxetine for months without success for months. ( I was switched to it from Celexa by a pain management provider
for treatment of chronic pelvic pain, because it has a “component” for that). If I had understood all the ramifications, I would Never have begun taking it. Brain fog. Sweating. Weird dreams. Blunted emotions. Sexual problems. It has been just awful trying to get off of it. I would not recommend it to anyone if you have other options. I practice mindfulness, and do many other positive things to manage my pain, but they haven’t helped to overcome the side effects of my Slowly paced withdrawal. Please do some research/reading before you head down that road. I hope this is helpful.

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