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78-year-old with 2 biopsies of cancer

Prostate Cancer | Last Active: Apr 5 7:56pm | Replies (10)

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Here's everything I have from his 2 biopsies: In 2024, it was Adenocarcinoma with Gleason score of 6 (3+3) in the left lateral base and 6 (3+3) in the left lateral mid. PSA was 4.7. In 2026, his PSA was 5.73. More targeted biopsies were made from a MRI and the 50% Adenocarcinoma in the left lateral mid was a Gleason score of 7 (3+4). A targeted lesion 1 was 35% Adenocarcinoma with a Gleason score of 7 (3+4). Pathologic Stage: T1c; Capsular Penetration: 23%; Decipher Score: 0.62. What would you recommend? We also have Proton Therapy here in Knoxville, TN, and we would probably go that route versus normal Radiation. Your thoughts on that, please and thank you.

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Replies to "Here's everything I have from his 2 biopsies: In 2024, it was Adenocarcinoma with Gleason score..."

@tbirddonna
Radiation could make sense. Five sessions of proton radiation could completely eliminate this problem. The only thing that concerns me is your statement of “ Capsular Penetration: 23%”.

The capsule is usually considered the prostate itself, If there’s actual penetration of the capsule, that means that the cancer has gotten out of it. The thing is, that would make it a T3a not a T1c.

Can you explain that conundrum?.