I have recently switched from Actemra to Tyenne due to insurance.

Posted by thereselefever @thereselefever, Aug 6, 2025

I have recently had to switch from Actemra injections to Tyenne due to insurance. Since the switch I am experiencing a lot of swelling in my feet and legs. Has anyone else had to make this switch and had similar experiences?

Interested in more discussions like this? Go to the Polymyalgia Rheumatica (PMR) Support Group.

bubbiebirder | @bubbiebirder | 5 days ago

Thanks for all the replies! I was diagnosed with PMR in February 2026, starting taper down from 20 mg of prednisone (OK on 17.5 mg), have Medicare Advantage with Kaiser through former employer, so only Tyenne approved. Rheumatologist wants to start after next round of lab tests. In our crazy system I couldn't even find out how much Actemra would cost if I paid myself, and copays for Tyenne are reasonable on my plan. Keeping fingers crossed...