@sue417 my rheumatologist didn’t tell me anything other than to take calcium and vitamin d after she told jr that I had it. The infusion center told me to take Tylenol and drink two glasses of water before I come at 2:30 pm. I did that. And I have taken Tylenol afterwards and every 6 hours since for the past 9 days since. I switched from fruit juices to straight water two weeks before I decided to try Reclast. And I did take Tylenol the day before for a headache.