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After Evenity

Posted by pami @pami, Jan 26, 2025

I will have my last injection of Evenity in two weeks. I don't want to have a Reclast infusion because I have had up to 5 in the past. I am concerned about starting Prolia for the remainder of my life. I am 70. I am considering Forteo because my insurance will pay for that rather than Tymlos. Any suggestions? I can't take bisphosphates. They wreck havoc on my stomach.

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kristie2 | @kristie2 | Aug 18, 2025
In reply to @kristie2 "Pami , Prolia will help with increasing bone density. After one year of Evenity I too..." + (show)
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Pami , Prolia will help with increasing bone density. After one year of Evenity I too needed more bone. I have had one injection so far of Prolia and shortly after my second injection with have a DEXA to see if I will move onto Reclast to lock my gains in.

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I just had my DEXA after being on Prolia for 1year. I am so disappointed my T score in my spine went from -3.3 to -3.2.

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jofall | @jofall | Aug 27, 2025

I have been diving into these threads because I just finished my year of Evenity with good results but still in the low threes everywhere. From what I have learned from my drs, Reclast would not be the right next step for me because while my gains were good, 20%, I am still over 3 and 56 so should try to build more. Prolia would be an option but I was thinking I should wait on that if the other bone builders might help. I have read of people doing Tymlos then Evenity but fewer the other way around. But two respected drs seem to think it’s safe and worth a try. It’s extremely unlikely I would see the more significant gains one would if it was their first drug, but the hope is that I will see more than with Prolia. Dr said he has seen up to 5% gains with Prolia after Evenity and expects Tymlos could be the same. I don’t know if I am just kicking the can down the road and should just go with Prolia.

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msturcken | @msturcken | Nov 26, 2025
In reply to @jcochrane3037 "I finished treatment with Evenity last month after 12 monthly doses. Post treatment DEXA showed 12%..." + (show)
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I finished treatment with Evenity last month after 12 monthly doses. Post treatment DEXA showed 12% increase in BMD at lumbar spine and 2%increase in BMD in total hip. T-score at lumbar spine went from -2.5 to -2.3 (osteoporotic to osteopenic). My rheumatologist recommended I take Prolia or Reclast within 3-4 weeks after completing the Evenity treatment to lock in the gains.I ended up taking Prolia because my Medicare Advantage plan removed Reclast from their formulary.
My only issues with Evenity were bruising and swelling at the injection site in each arm after each treatment and body aches and pains which have resolved with cessation.
My after insurance cost were $485 for each dose of Evenity (two injections) X 12 months for an out of pocket cost of $5820 for the drug and another $1200 or so for the administration fees. The Prolia injection was about $325 for the drug and $135 for cost of administration. Will have another Prolia injection in August.

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@jcochrane3037 I thought Medicare covered in office evenity shots. I hope so

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mjwg | @mjwg | Feb 12 10:41pm

I completed Evinity. My score went from -3 to -3.2. I just had a Reclast infusion. Has anyone else experienced no gain with Evinity? What did you do? Is Fotreo an option? I don’t want Prolia just yet.

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dallyup4 | @dallyup4 | 1 day ago
In reply to @naturegirl5 "@susanew As @gravity3 asked I am wondering what your doctor recommends? After I completed 12 months..." + (show)
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@susanew As @gravity3 asked I am wondering what your doctor recommends?

After I completed 12 months of Evenity my endocrinologist ordered a DEXA scan. I made significant gains in bone density in both my hip and lower spine. He explained that the gains with Evenity "fall off" if not "locked in" with another medication so within 6 weeks of completing the Evenity I had a Reclast infusion. My endocrinologist said the time frame between finishing Evenity and getting the Reclast infusion should be brief - no more than 6-8 weeks. The plan is for me to have another DEXA scan one year after the Reclast infusion (that will be in December, 2025) and then re-assess.

By the way, I had no side effects with Evenity or with Reclast.

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@naturegirl5
Can I ask if the DEXA scan comes out good in the next year, will you have to continue on Reclast and if so, how long?

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