Hi @floridaswan, and welcome to Mayo Clinic Connect! It sounds like your initial lipid panel needs some digging into the weeds to learn more about what is unique to you. You bring great questions and no doubt will benefit from more detailed testing.
APOA1 is associated with HDL and a risk for atherosclerosis. Mayo Clinic lab details are linked here and you may want to review to understand how it may impact your individual risk, particularly the “Clinical Information” section.
-Mayo Clinic Laboratories Apolipoprotein A1, Serum Overview
https://www.mayocliniclabs.com/test-catalog/Overview/607591
My experience is that this testing helps my doctor understand how my unique body functions, helping to figure out how to treat it. This would be a fantastic place for you to go next now that you have found out your HDL cholesterol is high.
Do you have other risk factors such as poor lifestyle, smoking, diabetes, high blood pressure, etc.? Is this something you think your doctor is familiar with?
@jlharsh // Hello Janell - what a coincidence that you posted on Apo A1, I just had my annual physical with a new doctor and he tested it. I was unfamiliar with this marker and did some reading, this explanation was helpful:
https://lolahealth.com/blogs/longevity/apolipoprotein-a1-blood-test-normal-ranges-causes-what-your-results-mean
TL:DR version - high Apo A1 is better. The ApoB / Apo A1 ratio is also important, lower is better.
I was greatly relieved to have both very high Apo A1 (190 mg/dl) and a very low ratio (0.29), that suggests my health routines and medications are working (edit: in 2021 my CAC score was 1124)