Hi @amaerica. Welcome to Connect. Thanks for joining the conversation about Factor V Leiden! Having inherited this genetic mutation from both sides of your parents really put you in higher risk for blood clots. From what you mentioned, it looks like you might have developed some clotting issues and are now on Xarelto to avoid future issues. So was this all discovered later in your life after a blood clot was detected? Did either your mom or dad have any clotting issues that you can recall?