Diagnosed with MF 3+/3 in January 2026. This after a frustrating 3 year journey of symptoms, missed by multiple (not Mayo) Specialists. In July 2025, I was Diagnosed with CMML-1 with low blasts. Local Oncologist referred me to Mayo in late December.
Mayo Oncologist picked up on the MF symptoms immediately. Ordered my third Bone Marrow Biopsy.
Cannot convey how thankful I am for the Oncologists at Mayo Clinic.

I am in process for BMT now, donors identified and testing underway. Hopefully to occur in about 2 months.
Im 63, otherwise healthy except Rheumatoid & Osteoarthritis. I had a Bone Density Scan in January, no problems.

Upon MF diagnosis, Mayo Oncologist put me on VONJO as I was having significant symptoms. In just two weeks, I felt like a new person, by 6 weeks (now) I feel better than I have in 3 years.
I consider VONJO nothing short of a miriacle drug.

I still have some Intense Itching and Bone Pain episodes but those symptoms are much easier to manage when you can breathe well, sleep well and my Spleen is not uncomfortable. After losing 50 pounds, I have gained back 5 pounds.

There are multiple medications to treat MF and symptoms. Your Oncologist will determine what you need, if anything. Wishing you the best possible outcome.