Anyone take Anastrozole every other day?

I'm surprised they're so adamant about not every other day. Considering that this one dose has a 50-hour half life. So you're doubling and tripling up every time you take a pill? Is that why you get sick later rather than at first. I am so tired I can't lift my head off the pillow. I sleep 24/7 almost. I have no energy to walk one small block to the pharmacy. I feel sick all the time. I swear to God this is not living. I do not even want to stay alive like this.

I'm surprised they're so adamant about not every other day. Considering that this one dose has a 50-hour half life. So you're doubling and tripling up every time you take a pill? Is that why you get sick later rather than at first. I am so tired I can't lift my head off the pillow. I sleep 24/7 almost. I have no energy to walk one small block to the pharmacy. I feel sick all the time. I swear to God this is not living. I do not even want to stay alive like this.

I am thinking about doing that. These cancer meds are hard on our bones. Logically a dosage every other day makes sense especially since the drug stays our system long enough to allow it to build up. Hmmmmm…. Would be interested in opinions of others on this med.

@jwmusic65
After 2 + years on anastrozole, I went EOD almost 3 months ago. I suggest we tell our doctors but currently I am changing my oncologist because of an office issue and certainly will discuss with my new physician.

I've posted this before in more detail. Summary: yes, you can reduce AI dosing to every other day, and yes, your blood estrogen will stay low. But, there is no research on whether the lower dose is as effective at preventing recurrence as daily dosing. In other words, you're in unknown territory if you reduce your dose. I apologize in advance if this sounds negative--and of course, wish you the best.

It has been almost 4 weeks since I went every other day with anastrozole. It affected my stomach and digestive tract when I started it the first few weeks ( 2 years ago) and experienced that again, but milder with lower dozing. Too early to tell for sure how I feel, but seems to be better with less brain fog and joint discomfort!
My decission may have be easier than for most since I had a score of 10% and 3% with AI. I believe they are doing cliinical trials on lower dosing now.