@betsyhase I'll just add my 2 cents worth to this interesting conversation. My husband and I were in the wine with dinner habit, probably, for me, a glass and a half 4 or 5 night a week. Since my diagnosis with PMR/GCA, I have almost cut out the wine. (He has also, for acid stomach pain.) Now, I only indulge when the meal is very special and seems to demand a glass of wine, maybe one glass every 2 weeks. The last time I had wine with a meal, it didn't seem to taste quite right, so it wasn't really special. I have never noticed any side effects to my glass of wine, but then, I'm not really a very observant person. But I don't think it makes any difference.