@lindaadele thanks. As I mentioned, my TSH was a bit high last year, and the doctor nor I could understand why. It is much higher this year, so I am trying to figure this out before I speak with my doctor in a few days. I came here hoping to find someone who has been through this, and might have some insight. I must keep the suppression, and for whatever reason, the Synthroid seems to be failing me after years of success.