@crbarefoot I have not started the MK4 at any dosage yet. I plan to discuss this with my cardiologists later this month and early April. Yes, you read that correctly. I see more than one cardiologist. One of them specializes in oncology and I was referred to her with my breast cancer diagnosis.

I have a feeling neither of these doctors will have an informed opinion on MK4 but still want to see what they might say. If they have no opinion about it, I will add MK4 but probably start at a lower dose.

I'd taken both MK4 and MK7 in the past but stopped when I developed afib first followed by breast cancer. People sometimes experience heart palpitations with MK7 so that was a no-no for me. During breast cancer treatment, I was advised to stop most supplements so just now figuring out what I can safely add.

Sorry I don't have any experience with high dose MK4, but there is another Mayo discussion on MK4 and MK7 dosages that may be helpful to you.
https://connect.mayoclinic.org/discussion/mk4-vs-mk7-for-osteoporosis/