My echo says I have Stage 1 diastolic dysfunction suggestive of abnormal relaxation. But that isn’t heart failure. By taking metoprolol and Lisinopril and eliquis with zetia I am managing it and since I have no problem with breathing or exercising and am not fatigued I am not wanted to add farxiga.

My sister is 10 years old than I am and she worse heart condition because she took tikosyn for her afib over 15 years ago and it caused her to have torsads which damaged her heart to the point she needed a pacemaker and defribulator. Then in about 2018 her endocrinologist put her on jaundice which is the sister drug to farxiga. It caused her ejection fraction to go down from 45 to 25 and she developed a severe kidney infection. Her cardiologist took her off the drug immediately. The side effects of these drugs are terrible if they happen to you and I have been told that there are complications from stopping them which are not good. Because there are other choices for heart failure I would prefer to avoid these medications like farxiga and Jardiance because they are the same thing. They were developed to treat diabetes. They didn’t work. So the companies marketed them for kidney failure. They are not working because they have so many terrible life threatening side effects. Then in 2024 the company funded a study to support use in heart failure patients. Read the studies. They had 2,000 some people and determined that 55% of them had a 2-3% chance of living longer but these were really sick people. Their data is very limited and not documented in the study’s for application to people who do not have diabetes or kidney failure and have moderate heart failure.

I am attaching a copy of the study. I think I will die of something. I had breast cancer last year and am on hormone blocking mediation which makes me tired and gives me joint pain because I don’t have any estrogen. I am 71. I will not go on another medication to “possibly” extend my life if it meanwhile can cause a whole host of other medical problems. But it is so helpful to see how other people are managing their heart issues with these drugs. I couldn’t take flexanide either - I felt terrible on it. I hope you do well without having to resort to more drugs. But we all have to make our own decisions based on the research and our bodies and doctors! Thanks so much for talking this through with me. So helpful.
https://www.nejm.org/doi/full/10.1056/NEJMoa1911303