@nisi I just posted this to someone asking about Jakafi and ET: “ I was placed on anagrelide for about 10 years until it was becoming no longer effective in keeping my platelets down and within the normal range. I was then prescribed Jakafi and it was very effective in managing my platelet level for about 10 years until my ET converted to Myelofibrosis. I was on 10 mg of Jakafi twice a day and never experienced any negative side effects.”

I was not on Jakafi much longer after My MF diagnosis, as my hemoglobin level was dropping below 7.0 and I became dependent on blood transfusions to keep it above a 7.0 threshold. For a while I was prescribed momelotinib which did help with the anemia, but I ultimately had a successful allogenic stem cell transplant in October 2024.

Good luck to your husband as he navigates his MF treatment.