I’m 75. 3 years ago I had RALP and immediately started on ADT – Lupron. After the first shot in the butt I could hardly sit for days. Shots never bother me; maybe it was the nurse. After that I insisted in the arm, and that was no problem. Stayed on Lupron for a year. Side effects tolerable. As many people report, side effects vary drastically from one individual to the next.
After a year off of ADT, my PSA was rising, so started up again with Lupron. Did a bunch of research comparing Lupron and Orgovyx and opted to make the switch halfway through the year. My greatest reason for making the switch is that Orgovyx (relugolix) is shown to have a lower risk of major cardiovascular events that Lupron (leuprolide). Beyond that I was hoping various side effects would be better - not so, for me. I can’t wait to get off these pills very soon, and see what happens.
As to specific side effects, I find it difficult attributing them to either ADT or my multitude of old age ailments.
As to cost, I never paid a penny for Lupron, but had to pay $1180 per month until I hit my Medicare out of pocket limit.
Sorry to be so wordy.